Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201638 | 0.87 | KMT2A (0.57) | PRKCHPRKCESYKKDM4EMEN1 | |
| SCHEMBL22201659 | 0.84 | PRKCH (0.50) | PRKCHPRKCESYKKDM4EMEN1 | |
| SCHEMBL22201280 | 0.83 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201557 | 0.82 | ALDH1A1 (0.59) | KDM4EMEN1KMT2ATGFBR1ABCB1 | |
| SCHEMBL22201586 | 0.82 | PRKCH (0.47) | PRKCHPRKCESYKKDM4EMEN1 | |
| SCHEMBL22201452 | 0.80 | PRKCH (0.58) | PRKCHPRKCESYKKDM4ETGFBR1 | |
| SCHEMBL22201455 | 0.77 | HPGD (0.51) | KDM4EMEN1KMT2AABCB1ABCG2 | |
| SCHEMBL22201641 | 0.76 | RIPK2 (0.55) | PRKCHPRKCESYKTGFBR1PRKD1 | |
| SCHEMBL22201430 | 0.76 | LATS1 (0.48) | KDM4EMEN1KMT2ATGFBR1ABCB1 | |
| SCHEMBL22201642 | 0.75 | PRKCH (0.53) | PRKCHPRKCESYKKDM4ETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |