Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201659 | 0.87 | PRKCH (0.50) | KMT2AKDM4EMEN1PRKCHPRKCE | |
| SCHEMBL22201470 | 0.87 | PRKCH (0.47) | KMT2AKDM4EMEN1PRKCHPRKCE | |
| SCHEMBL22201586 | 0.84 | PRKCH (0.47) | KMT2AKDM4EMEN1PRKCHPRKCE | |
| SCHEMBL22201295 | 0.82 | KDM4E (0.56) | KMT2AKDM4EMEN1RXFP1ALDH1A1 | |
| SCHEMBL22201452 | 0.82 | PRKCH (0.58) | KDM4EPRKCHPRKCESYKRXFP1 | |
| SCHEMBL22201471 | 0.81 | KDM4E (0.66) | KMT2AKDM4EMEN1RXFP1TGFBR1 | |
| SCHEMBL22201637 | 0.79 | PRKCH (0.50) | KMT2AKDM4EMEN1PRKCHPRKCE | |
| SCHEMBL22201641 | 0.79 | RIPK2 (0.55) | PRKCHPRKCESYKTGFBR1PRKD1 | |
| SCHEMBL22201642 | 0.78 | PRKCH (0.53) | KDM4EPRKCHPRKCESYKTGFBR1 | |
| SCHEMBL22201369 | 0.77 | LMNA (0.63) | KDM4EPRKCHPRKCESYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |