Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.86 |
| ▸ | TP53 | P04637 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32690563 | 0.87 | RXFP1 (0.90) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL4550115 | 0.83 | RXFP1 (0.69) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL2115751 | 0.77 | ALDH1A1 (0.78) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL4548108 | 0.74 | TP53 (0.62) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL16345051 | 0.74 | ROCK2 (0.65) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL15282209 | 0.74 | MAPT (0.56) | RXFP1TP53MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13091075 | 0.74 | ALDH1A1 (0.84) | TP53MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2611279 | 0.73 | RXFP1 (0.56) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL10132647 | 0.73 | PARP1 (0.66) | RXFP1TP53MAPTKMT2AMEN1 | |
| SCHEMBL8230874 | 0.73 | HTR3A (1.00) | MAPTSMN1; SMN2GAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |