Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 11/20 | 0.43 |
| ▸ | PRKCH | P24723 | 10/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 10/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 9/20 | 0.43 |
| ▸ | PRKCA | P17252 | 9/20 | 0.43 |
| ▸ | PRKCB | P05771 | 6/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.43 |
| ▸ | LATS1 | O95835 | 5/20 | 0.43 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201586 | 0.84 | PRKCH (0.47) | PRKCHPRKCEROCK2KDM4EMEN1 | |
| SCHEMBL22201432 | 0.82 | LATS1 (0.47) | LATS1LATS2KDM4E | |
| SCHEMBL22201404 | 0.79 | P2RX3 (0.38) | ROCK2KDM4EMEN1KMT2AP2RX3 | |
| SCHEMBL22201402 | 0.79 | MEN1 (0.36) | ROCK2KDM4EMEN1KMT2AP2RX3 | |
| SCHEMBL22201401 | 0.79 | KDM4E (0.36) | ROCK2KDM4EMEN1KMT2AP2RX3 | |
| SCHEMBL22201366 | 0.79 | MAPT (0.39) | CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL22201559 | 0.78 | HPGD (0.58) | KDM4EMEN1KMT2A | |
| SCHEMBL22201226 | 0.77 | PRKCH (0.37) | PRKCHPRKCEPRKD1CYP1A2P2RX3 | |
| SCHEMBL22201400 | 0.77 | KMT2A (0.37) | ROCK2KDM4EMEN1KMT2AP2RX3 | |
| SCHEMBL22201258 | 0.76 | ABCG2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |