Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 13/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201226 | 0.93 | PRKCH (0.37) | CYP1A2SYK | |
| SCHEMBL22201586 | 0.91 | PRKCH (0.47) | MAPTKDM4EHPGDABCG2ALDH1A1 | |
| SCHEMBL22201323 | 0.90 | SYK (0.38) | MAPTCYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL22201417 | 0.89 | P2RX3 (0.38) | CYP1A2EGFRSRCSYK | |
| SCHEMBL22201421 | 0.89 | SYK (0.36) | CYP1A2ABCG2ABCB1SYK | |
| SCHEMBL22201534 | 0.87 | PIK3CD (0.40) | SYK | |
| SCHEMBL22201327 | 0.87 | SYK (0.40) | ABCG2SYK | |
| SCHEMBL22201368 | 0.87 | SYK (0.45) | CYP1A2ABCG2ALDH1A1ABCB1SYK | |
| SCHEMBL22201489 | 0.86 | SYK (0.37) | MAPTCYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL22201622 | 0.86 | SYK (0.42) | CYP2C19SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |