Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201667 | 0.87 | ABCG2 (0.67) | ALDH1A1LMNACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL22201344 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAHPGDPOLBGSK3A | |
| SCHEMBL22201428 | 0.78 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDPOLBGSK3A | |
| SCHEMBL22201606 | 0.77 | TGFBR1 (0.66) | ALDH1A1LMNACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL414358 | 0.75 | CYP1A2 (1.00) | ALDH1A1LMNACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL22201581 | 0.75 | HPGD (0.81) | ALDH1A1LMNAHPGDPOLBGSK3A | |
| SCHEMBL22201663 | 0.72 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDPOLBGSK3A | |
| SCHEMBL22201440 | 0.72 | ABCG2 (0.74) | ALDH1A1LMNAHPGDPOLBGSK3A | |
| SCHEMBL1817920 | 0.70 | ALDH1A1 (0.68) | ALDH1A1LMNACYP1A2CYP3A4HSD17B10 | |
| SCHEMBL22201670 | 0.70 | HPGD (0.68) | ALDH1A1LMNAHPGDPOLBGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |