Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201660 | 0.84 | SYK (0.47) | SYKPRKCHPRKCE | |
| SCHEMBL22201451 | 0.80 | ABCG2 (0.56) | SYKPRKCHPRKCE | |
| SCHEMBL373789 | 0.69 | SYK (1.00) | SYK | |
| SCHEMBL22201437 | 0.68 | PRKCH (0.56) | SYKPRKCHPRKCE | |
| SCHEMBL11379518 | 0.68 | SYK (0.68) | SYKPRKCHPRKCE | |
| SCHEMBL22201369 | 0.66 | LMNA (0.63) | SYKPRKCHPRKCE | |
| SCHEMBL7265445 | 0.65 | SYK (0.61) | SYK | |
| SCHEMBL1549916 | 0.64 | SYK (0.47) | SYK | |
| SCHEMBL22271112 | 0.63 | SYK (0.68) | SYKPRKCHPRKCE | |
| SCHEMBL374100 | 0.63 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |