Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201451 | 0.84 | ABCG2 (0.56) | SYKPRKCHPRKCEABCG2GBA1 | |
| SCHEMBL22201712 | 0.84 | SYK (0.52) | SYKPRKCHPRKCE | |
| SCHEMBL22201369 | 0.69 | LMNA (0.63) | SYKPRKCHPRKCEABCG2GSK3B | |
| SCHEMBL373789 | 0.65 | SYK (1.00) | SYK | |
| SCHEMBL22201623 | 0.65 | ABCG2 (0.86) | ABCG2GBA1GSK3BMAPTMAPK1 | |
| SCHEMBL11379518 | 0.64 | SYK (0.68) | SYKPRKCHPRKCE | |
| SCHEMBL22201437 | 0.64 | PRKCH (0.56) | SYKPRKCHPRKCEMAPTMAPK1 | |
| SCHEMBL374100 | 0.62 | SYK (1.00) | SYK | |
| SCHEMBL10903401 | 0.61 | TAAR1 (0.44) | MAPT | |
| SCHEMBL373808 | 0.61 | SYK (0.73) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |