SCHEMBL22202094

SCHEMBL22202094

C/C(N)=C(\C)NC1=CCCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18726609 0.80 GAA (0.34)
SCHEMBL22368581 0.77
SCHEMBL5960697 0.76 SMN1; SMN2 (0.34)
SCHEMBL21991049 0.70
SCHEMBL10140100 0.69 ALDH1A1 (0.39)
SCHEMBL27644272 0.68 L3MBTL1 (0.44)
SCHEMBL13840985 0.68 KMT2A (0.40)
SCHEMBL25611951 0.68
SCHEMBL19454035 0.67
SCHEMBL24752220 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020142486-A1 KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2020-07-09 WO disclosed