Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 7/20 | 0.35 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112005 | 0.91 | CYP2C19 (0.32) | RAB9ADPP4LMNACYP2C19KDM4E | |
| SCHEMBL2247974 | 0.85 | HSD17B10 (0.35) | RAB9AHCRTR2DPP4DPP8DPP9 | |
| SCHEMBL6422872 | 0.81 | LMNA (0.36) | DPP4DPP8DPP9DPP7LMNA | |
| SCHEMBL7018182 | 0.81 | LMNA (0.36) | DPP4DPP8DPP9DPP7LMNA | |
| SCHEMBL20986580 | 0.81 | LMNA (0.35) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28673235 | 0.81 | KMT2A (0.38) | RAB9ALMNACYP2C19KDM4E | |
| SCHEMBL20914538 | 0.79 | DPP4 (0.34) | DPP4DPP8DPP9DPP7LMNA | |
| SCHEMBL21356962 | 0.77 | LMNA (0.40) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL2467671 | 0.73 | DPP4 (0.50) | DPP4LMNAKDM4EMAPT | |
| SCHEMBL23573046 | 0.73 | SMN1; SMN2 (0.34) | DPP4LMNAHSD17B10CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178057-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178057-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | REN, AGT, ACE | RAB9A 951/4885HCRTR2 902/4885DPP4 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.