Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986580 | 0.75 | LMNA (0.35) | DPP4ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL20986906 | 0.74 | PREP (0.50) | DPP4FKBP1AALDH1A1KDM4EMAPT | |
| SCHEMBL2220706 | 0.73 | RAB9A (0.38) | DPP4KDM4EMAPTLMNA | |
| SCHEMBL3807599 | 0.72 | RIPK1 (0.43) | DPP4FKBP1AALDH1A1KDM4ELMNA | |
| SCHEMBL6264470 | 0.72 | KDM4E (0.47) | DPP4EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL2430031 | 0.72 | USP30 (0.56) | DPP4EPHX2KDM4E | |
| SCHEMBL2430029 | 0.72 | USP30 (0.56) | DPP4EPHX2KDM4E | |
| SCHEMBL2247974 | 0.70 | HSD17B10 (0.35) | DPP4KDM4EMAPTLMNA | |
| SCHEMBL7018182 | 0.70 | LMNA (0.36) | DPP4LMNA | |
| SCHEMBL6422872 | 0.70 | LMNA (0.36) | DPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366698-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | Galapagos SAS (FR) | 2011-09-21 | — | — | EP | disclosed |