Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686690 | 0.83 | DPP4 (0.41) | KMT2AEPHX1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2220706 | 0.81 | RAB9A (0.38) | CYP2C19RAB9AKDM4ELMNA | |
| SCHEMBL4112005 | 0.75 | CYP2C19 (0.32) | EPHX1CYP2C19RAB9ACYP2D6KDM4E | |
| SCHEMBL19514122 | 0.72 | DPP4 (0.36) | CYP2C19ALDH1A1LMNAFAP | |
| SCHEMBL2247974 | 0.72 | HSD17B10 (0.35) | CYP2C19RAB9AKDM4ELMNAFAP | |
| SCHEMBL4108069 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL4108067 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL1609549 | 0.69 | EPHX2 (0.37) | KMT2AEPHX1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14370048 | 0.69 | P2RX7 (0.48) | KMT2AEPHX1RAB9A | |
| SCHEMBL3771274 | 0.69 | EPHX2 (0.37) | KMT2AEPHX1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924094-A | Ester-substituted ion channel blockers and methods of use thereof | 诺西恩医疗公司 | 2022-01-11 | — | — | CN | disclosed |