Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921220 | 0.84 | HRH3 (0.37) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL12474155 | 0.84 | FAAH (0.46) | CA2SMN1; SMN2FAAHGAAEPHX2 | |
| SCHEMBL22207996 | 0.84 | HRH3 (0.37) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL8524743 | 0.84 | FAAH (0.46) | CA2SMN1; SMN2FAAHGAAEPHX2 | |
| SCHEMBL22207898 | 0.84 | HRH3 (0.37) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL16094632 | 0.84 | FAAH (0.40) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL22208023 | 0.84 | HRH3 (0.37) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL21549536 | 0.84 | FAAH (0.40) | CA2SMN1; SMN2ALDH1A1FAAHGAA | |
| SCHEMBL31251083 | 0.84 | FAAH (0.46) | CA2SMN1; SMN2FAAHGAAEPHX2 | |
| SCHEMBL21385216 | 0.84 | ALDH1A1 (0.36) | CA2SMN1; SMN2ALDH1A1FAAHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215823-A1 | MEASUREMENT OF PERMEATION OF SMALL MOLECULES INTO GRAM NEGATIVE BACTERIA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-11-09 | — | — | WO | disclosed |
| EP-3908306-A1 | PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME | Yale University (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| WO-2020146470-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | CA2 2737/4885SMN1; SMN2 1455/4885ALDH1A1 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.