Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524743 | 1.00 | FAAH (0.46) | FAAHGAASLC6A5CNR1CNR2 | |
| SCHEMBL31251083 | 0.97 | FAAH (0.46) | FAAHGAASLC6A5CNR1CNR2 | |
| SCHEMBL21549536 | 0.88 | FAAH (0.40) | FAAHGAACNR1CNR2TLR2 | |
| SCHEMBL16094632 | 0.88 | FAAH (0.40) | FAAHGAACNR1CNR2TLR2 | |
| SCHEMBL17039698 | 0.87 | SLC6A5 (0.51) | FAAHGAASLC6A5CA12CA1 | |
| SCHEMBL9901520 | 0.86 | FAAH (0.44) | FAAHGAACNR1CNR2CA12 | |
| SCHEMBL12125335 | 0.85 | SLC6A5 (0.59) | FAAHSLC6A5CNR1CNR2TLR2 | |
| SCHEMBL18772401 | 0.85 | FAAH (0.67) | FAAHCNR1CNR2HPGDEPHX2 | |
| SCHEMBL22207993 | 0.84 | CA2 (0.45) | FAAHGAATLR2CA12CA1 | |
| SCHEMBL9901593 | 0.84 | FAAH (0.49) | FAAHGAACNR1CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341134-A2 | Covalent tethering of functional groups to proteins | Promega Corporation (US) | 2011-07-06 | — | — | EP | disclosed |
| US-7867726-B2 | Compositions comprising a dehalogenase substrate and a fluorescent label and methods of use | PROMEGA CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |