Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.46 |
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | TSPO | P30536 | 4/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207981 | 0.91 | F2 (0.43) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL22207974 | 0.75 | FNIP1 (0.53) | LTB4R2ALDH1A1HPGDNPSR1 | |
| SCHEMBL22374839 | 0.72 | FNIP1 (0.52) | ALDH1A1 | |
| SCHEMBL18426374 | 0.68 | LTB4R2 (0.74) | TSPOLTB4R2 | |
| SCHEMBL22207982 | 0.67 | FNIP1 (0.50) | ALDH1A1 | |
| SCHEMBL22375077 | 0.67 | FNIP1 (0.50) | ALDH1A1 | |
| SCHEMBL22375027 | 0.66 | FNIP1 (0.49) | ALDH1A1 | |
| SCHEMBL11562127 | 0.65 | TSHR (0.54) | TSPOALDH1A1HPGDNPSR1 | |
| SCHEMBL6800488 | 0.61 | TSPO (0.70) | TSPOLTB4R2ALDH1A1 | |
| SCHEMBL2729496 | 0.61 | FKBP1A (0.63) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908306-A1 | PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME | Yale University (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020146470-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |