Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799498 | 0.84 | TSPO (0.51) | TSPOALDH1A1SMN1; SMN2LTB4R2 | |
| SCHEMBL1068959 | 0.84 | MAOB (0.70) | ALOX5PTGS1PTGS2L3MBTL1MAOB | |
| SCHEMBL4517358 | 0.78 | FFAR1 (0.64) | ALOX5PTGS1PTGS2L3MBTL1MAOB | |
| SCHEMBL10922368 | 0.78 | RNF4 (0.67) | TSPOALDH1A1SMN1; SMN2LTB4R2 | |
| SCHEMBL9707249 | 0.77 | ALOX5 (1.00) | TSPOALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL6418344 | 0.77 | ALOX5 (0.74) | TSPOALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL5702266 | 0.77 | L3MBTL1 (0.63) | TSPOALOX5PTGS1PTGS2PTGES | |
| SCHEMBL6799059 | 0.76 | TSPO (0.46) | TSPOSMN1; SMN2 | |
| SCHEMBL28516316 | 0.76 | MAOB (0.68) | ALOX5PTGS1PTGS2L3MBTL1MAOB | |
| SCHEMBL9735930 | 0.76 | MAOB (0.68) | ALOX5PTGS1PTGS2L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |