Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.52 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | GPX4 | P36969 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207974 | 0.91 | FNIP1 (0.53) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL22207982 | 0.90 | FNIP1 (0.50) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL22375077 | 0.90 | FNIP1 (0.50) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL22375027 | 0.89 | FNIP1 (0.49) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL20456266 | 0.81 | ALDH1A1 (0.66) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL31104078 | 0.80 | FNIP1 (0.58) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL23817970 | 0.78 | GPX4 (0.54) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL21392964 | 0.74 | NPC1 (0.62) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL21401891 | 0.73 | RAB9A (0.58) | FNIP1FEM1BNPC1RAB9AMAPT | |
| SCHEMBL23126358 | 0.73 | MAOB (0.55) | NPC1RAB9AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | FNIP1 608/4885FEM1B 2109/4885NPC1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.