SCHEMBL222082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL221998	0.80	ABL1 (0.50)	—
	SCHEMBL2760411	0.78	PIK3CD (0.57)	PIK3CACYP19A1PIK3CDPIP5K1CPI4KA
	SCHEMBL1858197	0.77	CFTR (0.58)	CFTRCYP19A1CYP11B1CYP11B2NR4A2
	SCHEMBL12264114	0.75	PIK3CD (0.53)	PIK3CACYP19A1CYP11B1CYP11B2PIK3CD
	SCHEMBL12509852	0.75	PIK3CA (0.56)	PIK3CACYP19A1PIK3CDPIP5K1CPI4KA
	SCHEMBL984327	0.73	ILK (0.59)	CFTRKDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL222987	0.73	PIK3CD (0.51)	PIK3CACYP19A1CYP11B1CYP11B2PIK3CD
	SCHEMBL13188536	0.72	IKBKE (0.57)	CFTRCYP19A1CYP11B1CYP11B2NR4A2
	SCHEMBL223120	0.71	ABCB1 (0.52)	CFTRCYP19A1CYP11B1CYP11B2NR4A2
	SCHEMBL220748	0.71	ABL1 (0.52)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.