Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | PI4KA | P42356 | 2/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264114 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL12509852 | 0.80 | PIK3CA (0.56) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL222987 | 0.78 | PIK3CD (0.51) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL222082 | 0.78 | CFTR (0.48) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL222311 | 0.77 | PIK3CD (0.50) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL14347505 | 0.73 | ABL1 (0.53) | — | |
| SCHEMBL3710444 | 0.72 | PIK3CA (1.00) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL189244 | 0.72 | ASH1L (0.59) | PIK3CDPIK3CAPI4KAPI4KBPIP5K1C | |
| SCHEMBL13036623 | 0.71 | CYP2A6 (0.62) | SMN1; SMN2MKNK1MKNK2KDM4EMEN1 | |
| SCHEMBL13812998 | 0.71 | CYP2A6 (0.52) | SMN1; SMN2MKNK1MKNK2MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | PIK3CD 3480/4885PIK3CA 4048/4885PI4KA 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.