SCHEMBL222987

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL222287	0.79	CYP11B1 (0.55)	ALDH1A1MAPTCYP11B1CYP11B2CYP2A6
	SCHEMBL2760411	0.78	PIK3CD (0.57)	PIK3CDPIP5K1CPIK3CAPI4KAPI4KB
	SCHEMBL12264114	0.78	PIK3CD (0.53)	PIK3CDPIP5K1CPIK3CAPI4KAPI4KB
	SCHEMBL12509852	0.78	PIK3CA (0.56)	PIK3CDPIP5K1CPIK3CAPI4KAPI4KB
	SCHEMBL222296	0.77	ABL1 (0.50)	—
	SCHEMBL1359189	0.74	CYP11B1 (0.51)	ALDH1A1MAPTCYP11B1CYP11B2CYP2A6
	SCHEMBL29580441	0.73	TDP1 (0.67)	ALDH1A1MAPTCYP11B1CYP11B2CYP2A6
	SCHEMBL77083	0.73	TDP1 (0.67)	ALDH1A1MAPTCYP11B1CYP11B2CYP2A6
	SCHEMBL222082	0.73	CFTR (0.48)	PIK3CDPIP5K1CPIK3CAPI4KAPI4KB
	SCHEMBL5036431	0.72	CHEK2 (0.50)	ALDH1A1CYP11B1CYP11B2CYP2A6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.