Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725215 | 1.00 | AKR1C3 (0.42) | AKR1C3AKR1C1SLC9A1TDP1HTT | |
| SCHEMBL28725165 | 0.88 | SLC9A1 (0.42) | SLC9A1TDP1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22209882 | 0.88 | SLC9A1 (0.42) | SLC9A1TDP1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22194699 | 0.78 | XDH (0.39) | TDP1HTTSMN1; SMN2XDHL3MBTL1 | |
| SCHEMBL22194693 | 0.78 | XDH (0.39) | TDP1HTTSMN1; SMN2XDHL3MBTL1 | |
| SCHEMBL28725213 | 0.76 | AKR1C3 (0.43) | AKR1C3AKR1C1KDM1AALDH1A1GRIN2B | |
| SCHEMBL20495435 | 0.72 | PARP1 (0.42) | SLC9A1TDP1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL20495432 | 0.72 | PARP1 (0.42) | SLC9A1TDP1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22209812 | 0.72 | AKR1C3 (0.46) | AKR1C3AKR1C1SLC9A1KDM1AKDM4E | |
| SCHEMBL28725144 | 0.72 | AKR1C3 (0.46) | AKR1C3AKR1C1SLC9A1KDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | TRPA1, TRPV1, TRPV3 | AKR1C3 705/4885AKR1C1 943/4885SLC9A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.