Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 4/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209791 | 0.83 | AR (0.54) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL22210063 | 0.82 | PRKCZ (0.37) | TRPA1CHRM2CHRM1CHRM4 | |
| SCHEMBL22210152 | 0.81 | DPP4 (0.42) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL4635204 | 0.81 | DPP4 (0.47) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL22209797 | 0.78 | TRPA1 (0.40) | TRPA1CHRM2CHRM5CHRM1CYP11B2 | |
| SCHEMBL22209792 | 0.76 | HRH3 (0.49) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL22210038 | 0.75 | PRKCZ (0.41) | TRPA1 | |
| SCHEMBL22210160 | 0.74 | DRD2 (0.51) | TRPA1CHRM2CHRM1 | |
| SCHEMBL19692631 | 0.74 | AR (0.47) | CHRM2ARCHRM5CHRM1CHRM4 | |
| SCHEMBL22210394 | 0.74 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | GENENTECH, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711004-B2 | Oxadiazole transient receptor potential channel inhibitors | TRPA1, TRPV1, TRPV3 | DPP4 2718/4885PREP 2995/4885DPP8 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.