SCHEMBL22214862

SCHEMBL22214862

CC1(C)c2ccccc2N(c2ccc(P3(=O)c4ccccc4C(=O)c4ccccc43)cc2)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 11/20 0.39
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 3/20 0.35
GAA P10253 3/20 0.35
MAPT P10636 3/20 0.35
NPSR1 Q6W5P4 3/20 0.34
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34
CES1 P23141 1/20 0.34
USP2 O75604 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SCN2A Q99250 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22214863 0.85 ALDH1A1 (0.35) PGRALDH1A1GAANPSR1CES2
SCHEMBL21149443 0.82 MAPT (0.33) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL19797393 0.79 ALDH1A1 (0.33) PGRMEN1KMT2AALDH1A1MAPT
SCHEMBL24974233 0.79 PGR (0.35) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL21149963 0.78 MEN1 (0.31) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL24246794 0.78 MEN1 (0.31) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL22969897 0.78 PGR (0.44) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL24974118 0.78 PGR (0.35) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL24974225 0.77 ITGB2 (0.33) PGRMEN1KMT2AALDH1A1GAA
SCHEMBL22063753 0.76 ITGB2 (0.34) PGRMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851292-B2 Dark blue light thermally activated delayed fluorescence (TADF) material and application thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-12-01 US disclosed
US-20200224089-A1 DARK BLUE LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL AND APPLICATION THEREOF WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851292-B2 Dark blue light thermally activated delayed fluorescence (TADF) material and application thereof TEAD2, MYO1F, GTF2F1 PGR 4217/4885MEN1 3998/4885KMT2A 3538/4885
US-20200224089-A1 DARK BLUE LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL AND APPLICATION THEREOF TEAD2, MYO1F, GTF2F1 PGR 4217/4885MEN1 3998/4885KMT2A 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.