Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.39 |
| ▸ | ADH1A | P07327 | 4/20 | 0.39 |
| ▸ | ADH7 | P40394 | 3/20 | 0.39 |
| ▸ | ADH1C | P00326 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12418621 | 0.91 | ALDH1A1 (0.39) | ADH1BADH1AADH7ADH1CKMT2A | |
| SCHEMBL24259722 | 0.83 | HPGD (0.50) | ADH1BADH1AADH7ADH1CKMT2A | |
| SCHEMBL26151157 | 0.79 | MCL1 (0.45) | KMT2AALDH1A1MEN1USP2TSHR | |
| SCHEMBL23059829 | 0.78 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1HPGDUSP2 | |
| SCHEMBL16588651 | 0.77 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1USP2CA1 | |
| SCHEMBL14896643 | 0.77 | MEN1 (0.62) | ADH1BADH1AADH7ADH1CKMT2A | |
| SCHEMBL12410354 | 0.76 | USP2 (0.36) | ADH1BADH1AADH7ADH1CKMT2A | |
| SCHEMBL20310079 | 0.76 | CASP2 (0.47) | KMT2AMEN1HPGDEPHX1TP53 | |
| SCHEMBL25574095 | 0.76 | CA1 (0.41) | KMT2AALDH1A1MEN1HPGDUSP2 | |
| SCHEMBL8657660 | 0.74 | MCL1 (0.41) | KMT2AALDH1A1HPGDUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145227-A1 | COMPLEX COMPRISING LIGAND, SPACER, PEPTIDE LINKER, AND BIOMOLECULE | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |
| WO-2020145228-A1 | COMPLEX COMPRISING LIGAND AND CEACAM5 ANTIBODY FAB FRAGMENT | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |