SCHEMBL2222065

SCHEMBL2222065

CC(C)(C)C=C(F)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.39
GRIK1 P39086 1/20 0.38
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9257276 1.00 GABRR1 (0.39) GABRR1GRIK1ALDH1A1TSHR
SCHEMBL9257272 1.00 GABRR1 (0.39) GABRR1GRIK1ALDH1A1TSHR
SCHEMBL4602718 0.77 GABRR1 (0.34) GABRR1
SCHEMBL4602714 0.77 GABRR1 (0.34) GABRR1
SCHEMBL9956486 0.71 GRIK1 (0.40) GRIK1ALDH1A1TSHR
SCHEMBL8518270 0.71 GRIK1 (0.40) GRIK1ALDH1A1TSHR
SCHEMBL28443096 0.70 GABRR1 (0.38) GABRR1
SCHEMBL15546709 0.69
SCHEMBL136678 0.69
SCHEMBL264893 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177454-A1 RESIST MATERIAL AND PATTERN FORMATION METHOD USING THE RESIST MATERIAL PANASONIC CORPORATION (JP) 2011-07-21 US claimed
EP-4201408-B1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2025-06-25 EP disclosed
EP-4201408-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA Vifor (International) Ltd. (CH) 2023-06-28 EP disclosed
EP-3431094-B1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2022-12-07 EP disclosed
US-20220000906-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR (INTERNATIONAL) LTD. (CH) 2022-01-06 US disclosed
US-20200289550-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA RELYPSA, INC. 2020-09-17 US disclosed
CN-110051686-A Composition comprising cross-linked cationic conjugated polymer 瑞立普萨公司 2019-07-26 CN disclosed
EP-2365988-B2 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2019-07-03 EP disclosed
EP-3431094-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA Vifor Pharma Innovation Ltd. (CH) 2019-01-23 EP disclosed
EP-2957286-B1 COMPOSITIONS COMPRISING CROSSLINKED CATION EXCHANGE POLYMERS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2018-11-21 EP disclosed
US-20100104527-A1 TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES RELYPSA, INC. (US) 2010-04-29 US disclosed
US-7687991-B2 Organic electroluminescence device CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
WO-2010022381-A1 TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES RELYPSA, INC. (US) 2010-02-25 WO disclosed
WO-2010022383-A2 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA RELYPSA, INC. (US) 2010-02-25 WO disclosed
US-20080280876-A1 Novel oxadiazole compounds ABBVIE INC. 2008-11-13 US disclosed
US-20080012473-A1 ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2008-01-17 US disclosed
EP-1449860-A1 NOVEL FLUOROPOLYMER, RESIST COMPOSITIONS CONTAINING THE SAME, AND NOVEL FLUOROMONOMERS Daikin Industries, Ltd. (JP) 2004-08-25 EP disclosed
US-5466710-A Heterobicycloalkanes as pesticidal compounds ROUSSEL UCLAF (FR) 1995-11-14 US disclosed
US-5116862-A Acetylenic trithiabicyclo(2.2.2)octanes THE WELLCOME FOUNDATION LIMITED (GB) 1992-05-26 US disclosed
EP-0300797-A1 Pesticidal compounds ROUSSEL UCLAF (FR) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104527-A1 TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES KCNJ1, KCNN3, KCNJ11 GABRR1 1465/4885GRIK1 224/4885ALDH1A1 4815/4885
US-20080280876-A1 Novel oxadiazole compounds S1PR3, S1PR1, S1PR2 GABRR1 193/4885GRIK1 298/4885ALDH1A1 4044/4885
US-20220000906-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA ABCB11, SLC26A3, KCNN3 GABRR1 1132/4885GRIK1 259/4885ALDH1A1 4842/4885
US-20200289550-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA ABCB11, SLC26A3, KCNN3 GABRR1 1132/4885GRIK1 259/4885ALDH1A1 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.