Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986602 | 0.88 | HTR6 (0.47) | HTR6JAK2BRD4 | |
| Hydrochloric Acid SCHEMBL2268842 | 0.87 | HTR6 (0.46) | HTR6JAK2BRD4 | |
| SCHEMBL2278320 | 0.86 | HTR6 (0.48) | HTR6JAK2MEN1KMT2ABRD4 | |
| SCHEMBL2223299 | 0.85 | HTR6 (0.42) | HTR6IDH2JAK2 | |
| SCHEMBL2224695 | 0.85 | HTR6 (0.41) | HTR6IDH2JAK2MAPT | |
| SCHEMBL2278467 | 0.85 | HTR6 (0.41) | HTR6IDH2MAPTLCKMAPK14 | |
| SCHEMBL14354294 | 0.84 | MAPT (0.52) | HTR6POLBMAPTSMN1; SMN2 | |
| SCHEMBL2271717 | 0.84 | HTR6 (0.41) | HTR6JAK2BRD4 | |
| SCHEMBL2226307 | 0.82 | KCNH2 (0.49) | HTR6MAPT | |
| SCHEMBL2222384 | 0.82 | TDO2 (0.44) | HTR6JAK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | claimed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | claimed |
| US-9018231-B2 | Sulfone compounds as 5-HT6 receptor ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2015-04-28 | — | — | US | disclosed |
| US-20130005709-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2013-01-03 | — | — | US | disclosed |
| EP-2521714-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011083487-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005709-A1 | SULFONE COMPOUNDS AS 5-HT6 RECEPTOR LIGANDS | HTR6, HTR5A, HTR1A | HTR6 1/4885IDH2 4706/4885JAK2 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.