Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | GRM5 | P41594 | 5/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276927 | 0.88 | SMN1; SMN2 (0.51) | RAB9AGRM5FPR2LMNAALDH1A1 | |
| SCHEMBL3324587 | 0.87 | LMNA (0.58) | RAB9AGRM5LMNAALDH1A1CNR2 | |
| SCHEMBL2279802 | 0.81 | P2RX7 (0.56) | RAB9ALMNAALDH1A1CNR2SMN1; SMN2 | |
| SCHEMBL10152384 | 0.79 | GRM5 (0.59) | RAB9AGRM5FPR2LMNAALDH1A1 | |
| SCHEMBL12516066 | 0.78 | LMNA (0.46) | RAB9AGRM5FPR2LMNAALDH1A1 | |
| SCHEMBL30794648 | 0.77 | GRM5 (0.73) | GRM5FPR2CNR2MEN1KMT2A | |
| SCHEMBL2221951 | 0.77 | GRM5 (0.73) | GRM5FPR2CNR2MEN1KMT2A | |
| SCHEMBL9960850 | 0.76 | GRM5 (0.50) | RAB9AGRM5FPR2LMNAALDH1A1 | |
| SCHEMBL2269402 | 0.73 | SMN1; SMN2 (0.50) | RAB9ALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1578461 | 0.72 | GRM5 (0.50) | GRM5FPR2CNR2NPC1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |