SCHEMBL2222669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2222903	0.87	HTR3E (0.47)	MEN1KMT2AHTR3EHTR3BHTR1A
	SCHEMBL2224886	0.86	MEN1 (0.50)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2223370	0.85	MEN1 (0.49)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2223195	0.83	KDM4E (0.47)	MEN1KMT2AALDH1A1LMNAKDM4E
	SCHEMBL2222316	0.82	MEN1 (0.47)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2222338	0.82	MEN1 (0.47)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2224506	0.81	MEN1 (0.44)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2222851	0.80	MAPT (0.57)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL2222887	0.80	LMNA (0.46)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL14554261	0.80	NPC1 (0.50)	MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.