SCHEMBL2222887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15678973	0.94	LMNA (0.48)	LMNAMAPTMEN1KMT2APRKAA2
	SCHEMBL12517250	0.90	KMT2A (0.47)	MAPTMEN1KMT2AATMCYP1A2
	SCHEMBL2225300	0.89	ALDH1A1 (0.43)	MEN1KMT2ACYP1A2CYP2D6CYP2C9
	SCHEMBL14554261	0.88	NPC1 (0.50)	LMNAMAPTMEN1KMT2AKDM4E
	SCHEMBL2223195	0.87	KDM4E (0.47)	LMNAMEN1KMT2AKDM4EFAAH
	SCHEMBL2222796	0.87	FAAH (0.48)	LMNAMEN1KMT2AKDM4ECYP1A2
	SCHEMBL14554259	0.85	KMT2A (0.46)	LMNAMAPTMEN1KMT2ACYP1A2
	SCHEMBL2222732	0.83	HTR7 (0.48)	LMNAMAPTMEN1KMT2AKDM4E
	SCHEMBL2222103	0.82	MEN1 (0.41)	LMNAMAPTMEN1KMT2AATM
	SCHEMBL2226124	0.82	MAPT (0.68)	LMNAMAPTPRKAA2KDM4EFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.