Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219074 | 1.00 | DGKA (0.51) | DGKAGNAI3GNAO1GNAI1PAM | |
| Hydrochloric Acid SCHEMBL2221631 | 0.98 | GNAI3 (0.52) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL2263737 | 0.92 | DGKA (0.50) | DGKAMAPTALDH1A1 | |
| SCHEMBL2219724 | 0.92 | DGKA (0.50) | DGKAMAPTALDH1A1 | |
| SCHEMBL20057624 | 0.85 | DGKA (0.57) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL11337135 | 0.85 | DGKA (0.57) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL11337142 | 0.85 | DGKA (0.57) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL11779963 | 0.84 | HRH2 (0.60) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL11712690 | 0.84 | HRH2 (0.60) | DGKAGNAI3GNAO1GNAI1PAM | |
| SCHEMBL17281301 | 0.81 | DGKA (0.51) | DGKAPAMTSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |