Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222284 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30731286 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Hydrogen Sulfide SCHEMBL28270010 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL16151415 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Sulfamide SCHEMBL28719576 | 0.81 | HTT (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Biphenyl SCHEMBL28350717 | 0.80 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6517140 | 0.77 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Phenanthridine SCHEMBL8604527 | 0.73 | GPR3 (0.77) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Ethoxycarbonyl Group SCHEMBL28038348 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| Sulfanilamide SCHEMBL27528584 | 0.71 | CYP2C9 (0.55) | SMN1; SMN2ALDH1A1HTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715458-A | Cancer vaccine compositions and methods of use thereof | 华盛顿大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-106456735-A | Breast and ovarian cancer vaccines | 华盛顿大学商业中心 | 2017-02-22 | — | — | CN | disclosed |