SCHEMBL2222873

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27887000	0.83	CYP3A4 (0.57)	CYP3A4HTR6HTR2AHTR2CCYP2D6
	SCHEMBL2170725	0.82	CYP3A4 (0.50)	CYP3A4HTR6ALDH1A1SMN1; SMN2POLB
	SCHEMBL2223822	0.82	HTR6 (0.41)	HTR6ALDH1A1SMN1; SMN2POLBMAPT
	SCHEMBL4629472	0.81	VCP (0.46)	CYP3A4HTR6HTR2AHTR2CKCNH2
	SCHEMBL27886995	0.81	CYP3A4 (0.49)	CYP3A4HTR6HTR2AHTR2CCHRM2
	SCHEMBL2268905	0.78	HTR6 (0.59)	CYP3A4HTR6ALDH1A1MAPTL3MBTL1
	SCHEMBL2222879	0.78	NSD2 (0.53)	CYP3A4HTR6ALDH1A1POLBHTR2A
	SCHEMBL2223943	0.76	CYP3A4 (0.47)	CYP3A4HTR6HTR2AHTR2CKCNH2
	SCHEMBL16986613	0.76	CYP3A4 (0.49)	CYP3A4HTR6ALDH1A1SMN1; SMN2HTR2A
	SCHEMBL4630060	0.76	HRH4 (0.42)	CYP3A4HTR6HTR2AHTR2CKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.