Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19582824 | 0.89 | MEN1 (0.44) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL20921400 | 0.78 | PTGS2 (0.34) | ALDH1A1 | |
| SCHEMBL10703576 | 0.77 | MEN1 (0.38) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL5446381 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL22517795 | 0.75 | PTGS2 (0.40) | ALDH1A1 | |
| SCHEMBL3922804 | 0.75 | PTGS2 (0.43) | ALDH1A1 | |
| SCHEMBL22518095 | 0.73 | PTGS2 (0.33) | HIF1AALDH1A1 | |
| SCHEMBL10403702 | 0.73 | — | — | |
| SCHEMBL10403701 | 0.73 | — | — | |
| SCHEMBL11300343 | 0.72 | ALDH1A1 (0.46) | MEN1LMNABLMHBBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587403-B1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2021-12-28 | — | — | US | disclosed |
| CN-107652239-B | N-substituted imidazole carboxylic ester compound, preparation method and application | 四川大学华西医院 | 2020-08-04 | — | — | CN | disclosed |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | NR3C1, CYP2E1, CYP3A5 | MEN1 2309/4885LMNA 2836/4885BLM 4696/4885 |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | CHRM1, CYP2C18, CYP2E1 | MEN1 2037/4885LMNA 1556/4885BLM 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.