Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895861 | 0.83 | CA2 (0.55) | CA2CA4CA5ACFTRALOX15 | |
| SCHEMBL23352340 | 0.79 | CA2 (0.50) | CA2CA4CA5ACFTRALOX15 | |
| SCHEMBL8847094 | 0.79 | KMT2A (0.53) | CA2CA4CA5ACFTRALOX15 | |
| Bicarbonate SCHEMBL28587476 | 0.78 | CA2 (0.62) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL9003185 | 0.78 | CA2 (0.89) | CA2CA4CA5ACFTRALOX15 | |
| SCHEMBL17023658 | 0.77 | CA2 (0.48) | CA2CA4CA5ACFTRALOX15 | |
| SCHEMBL58814 | 0.77 | ALDH1A1 (0.52) | CA2CA4CA5ACFTRALOX15 | |
| SCHEMBL17446544 | 0.77 | CA2 (0.48) | CA2CA4CA5ACFTRTSHR | |
| SCHEMBL10054245 | 0.77 | USP2 (0.50) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL34998 | 0.77 | CA2 (1.00) | CA2CA4CA5ACFTRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815258-B2 | Phosphine oxides reduction | RHODIA OPERATIONS (FR) | 2020-10-27 | — | — | US | claimed |
| US-20200231613-A1 | PHOSPHINE OXIDES REDUCTION | SPECIALTY OPERATIONS FRANCE (FR) | 2020-07-23 | — | — | US | claimed |
| US-10815258-B2 | Phosphine oxides reduction | RHODIA OPERATIONS (FR) | 2020-10-27 | — | — | US | disclosed |
| US-20200231613-A1 | PHOSPHINE OXIDES REDUCTION | SPECIALTY OPERATIONS FRANCE (FR) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815258-B2 | Phosphine oxides reduction | PHOSPHO1, PSPH, PTEN | CA2 1666/4885CA4 344/4885CA5A 492/4885 |
| US-20200231613-A1 | PHOSPHINE OXIDES REDUCTION | PHOSPHO1, PSPH, PTEN | CA2 1666/4885CA4 344/4885CA5A 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.