SCHEMBL17023658

SCHEMBL17023658

O=C(c1ccccc1C(=O)P(=O)(c1ccccc1)c1ccccc1)P(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA5A P35218 1/20 0.48
ALDH1A1 P00352 6/20 0.46
ALOX15 P16050 2/20 0.46
USP2 O75604 2/20 0.45
CFTR P13569 1/20 0.43
KMT2A Q03164 6/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HSP90AA1 P07900 1/20 0.42
MEN1 O00255 4/20 0.41
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 2/20 0.40
ESR1 P03372 1/20 0.40
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
PKM P14618 1/20 0.39
PDE3A Q14432 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57823 0.86 HPGD (0.50) ALDH1A1KMT2ATSHRGAAKDM4E
SCHEMBL19253581 0.86 MAPT (0.55) CA2CA4CA5AALDH1A1ALOX15
SCHEMBL4181722 0.84 BCAT2 (0.53) ALDH1A1KMT2AHSP90AA1MEN1TSHR
SCHEMBL16403509 0.84 KMT2A (0.44) ALDH1A1USP2CFTRKMT2AL3MBTL1
SCHEMBL68477 0.82 NR4A1 (0.58) ALDH1A1KMT2AL3MBTL1MEN1TDP1
SCHEMBL28788708 0.82 TERT (0.45) CA2CA4ALDH1A1ALOX15KMT2A
SCHEMBL487265 0.81 LMNA (0.45) ALDH1A1KMT2AMEN1TSHRTDP1
SCHEMBL27617003 0.81 KMT2A (0.38) CA2CA4CA5AALDH1A1ALOX15
SCHEMBL8417547 0.81 TSHR (0.56) ALDH1A1KMT2AMEN1TSHRNPC1
SCHEMBL27973884 0.81 NPSR1 (0.47) CA2CA4CA5AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689338-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2020-08-05 EP claimed
EP-3110405-A2 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2017-01-04 EP claimed
WO-2015130707-A2 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE, INC. (US) 2015-09-03 WO claimed
US-20150238754-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION OCULEVE, INC. 2015-08-27 US claimed
EP-4194523-A1 CYANOACRYLATE ADHESIVE COMPOSITION Cuantum Medical Cosmetics, S.L. (ES) 2023-06-14 EP disclosed
EP-3689338-A1 POLYMER FORMULATIONS FOR NASOLACRIMAL STIMULATION Oculeve, Inc. (US) 2020-08-05 EP disclosed