Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353940 | 0.74 | GRIA2 (0.48) | SMN1; SMN2MTNR1BMTNR1AKDM4EGRIA2 | |
| SCHEMBL10709191 | 0.70 | SMN1; SMN2 (0.80) | SMN1; SMN2MTNR1BMTNR1AKDM4EMEN1 | |
| SCHEMBL29929943 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2MTNR1BMTNR1AKDM4EMEN1 | |
| SCHEMBL1061713 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2MTNR1BMTNR1AKDM4EMEN1 | |
| SCHEMBL13167638 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2MTNR1BMTNR1AKDM4EMEN1 | |
| SCHEMBL30053231 | 0.70 | SMN1; SMN2 (0.72) | SMN1; SMN2MTNR1BMTNR1AKDM4EMEN1 | |
| SCHEMBL11001305 | 0.69 | KDM4E (0.44) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL11049862 | 0.68 | SMN1; SMN2 (0.77) | SMN1; SMN2MTNR1BMTNR1AKDM4EHTT | |
| SCHEMBL4608736 | 0.66 | SMN1; SMN2 (0.73) | SMN1; SMN2MTNR1BMTNR1AKDM4EHTT | |
| SCHEMBL25659971 | 0.66 | RYR2 (0.45) | KDM4EHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |