Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353944 | 0.92 | GRIA2 (0.44) | GRIA2MTNR1BMTNR1ASMN1; SMN2ADRA1D | |
| SCHEMBL2353218 | 0.92 | ADRA1D (0.46) | GRIA2ADRA1DSLC10A2KDM4EPOLB | |
| SCHEMBL2353968 | 0.89 | GRIA2 (0.47) | GRIA2ADRA1DPOLB | |
| SCHEMBL2357409 | 0.86 | GRIA2 (0.35) | GRIA2SMN1; SMN2ADRA1DSLC10A2KDM4E | |
| SCHEMBL2352846 | 0.83 | ADRA1D (0.42) | GRIA2ADRA1DSLC10A2 | |
| SCHEMBL2351722 | 0.83 | MAOA (0.35) | GRIA2ADRA1D | |
| SCHEMBL2354007 | 0.76 | MMP2 (0.46) | MTNR1BMTNR1ASMN1; SMN2ADRA1DNPC1 | |
| SCHEMBL2354383 | 0.75 | CA1 (0.36) | GRIA2SMN1; SMN2ADRA1DGALR1 | |
| SCHEMBL2222984 | 0.74 | SMN1; SMN2 (0.44) | GRIA2MTNR1BMTNR1ASMN1; SMN2KDM4E | |
| SCHEMBL2355589 | 0.72 | ADRA1D (0.40) | GRIA2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |