SCHEMBL4608736

SCHEMBL4608736

COc1ccc(Oc2cccc(Oc3ccc(OC)cc3)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.73
LTA4H P09960 2/20 0.73
ALDH1A1 P00352 3/20 0.60
MEN1 O00255 1/20 0.60
MITF O75030 1/20 0.60
GAA P10253 1/20 0.60
MAPT P10636 1/20 0.60
GFER P55789 1/20 0.60
KMT2A Q03164 1/20 0.60
NLRP1 Q9C000 1/20 0.60
NOD2 Q9HC29 1/20 0.60
MTNR1B P49286 5/20 0.58
MTNR1A P48039 3/20 0.58
KDM4E B2RXH2 1/20 0.56
HTT P42858 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049862 0.98 SMN1; SMN2 (0.77) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL15834450 0.95 LTA4H (0.82) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL10709191 0.95 SMN1; SMN2 (0.80) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL1061713 0.90 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL30053231 0.90 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL29929943 0.90 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL13167638 0.90 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL12260798 0.89 SMN1; SMN2 (0.61) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL491308 0.88 SMN1; SMN2 (0.70) SMN1; SMN2LTA4HALDH1A1MEN1MITF
SCHEMBL3294529 0.87 ACHE (0.72) SMN1; SMN2LTA4HALDH1A1MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-06-25 US disclosed
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-06-25 US disclosed
US-9051229-B2 Transition metal catalysts for C—O hydrogenolysis and hydrodeoxygenation GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2015-06-09 US disclosed
US-20140179954-A1 TRANSITION METAL CATALYSTS FOR C-O HYDROGENOLYSIS AND HYDRODEOXYGENATION GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2014-06-26 US disclosed
US-7425358-B2 Copolycarbonates having improved flowability BAYER MATERIALSCIENCE AG (DE) 2008-09-16 US disclosed
EP-1749043-B1 COPOLYCARBONATES WITH AN IMPROVED FLUIDITY BAYER MATERIALSCIENCE AG (DE) 2008-07-30 EP disclosed
EP-1749043-A1 COPOLYCARBONATES WITH AN IMPROVED FLUIDITY Bayer MaterialScience AG (DE) 2007-02-07 EP disclosed
WO-2005113639-A1 COPOLYCARBONATES WITH AN IMPROVED FLUIDITY BAYER MATERIALSCIENCE AG (DE) 2005-12-01 WO disclosed
US-20050250915-A1 Copolycarbonates having improved flowability BAYER MATERIALSCIENCE AG 2005-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140179954-A1 TRANSITION METAL CATALYSTS FOR C-O HYDROGENOLYSIS AND HYDRODEOXYGENATION HMOX1, HAO2, PPOX SMN1; SMN2 3473/4885LTA4H 2213/4885ALDH1A1 2882/4885
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom TPR, AS3MT, ASF1A SMN1; SMN2 3987/4885LTA4H 2586/4885ALDH1A1 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.