SCHEMBL10709191

SCHEMBL10709191

COc1cccc(Oc2ccc(Oc3cccc(OC)c3)cc2)c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.80
LTA4H P09960 1/20 0.65
MTNR1B P49286 9/20 0.62
MTNR1A P48039 6/20 0.62
ALDH1A1 P00352 2/20 0.60
MEN1 O00255 1/20 0.60
MITF O75030 1/20 0.60
GAA P10253 1/20 0.60
MAPT P10636 1/20 0.60
GFER P55789 1/20 0.60
KMT2A Q03164 1/20 0.60
NLRP1 Q9C000 1/20 0.60
NOD2 Q9HC29 1/20 0.60
PGR P06401 3/20 0.57
ACHE P22303 1/20 0.56
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049862 0.98 SMN1; SMN2 (0.77) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL4608736 0.95 SMN1; SMN2 (0.73) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL13167638 0.95 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL1061713 0.95 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL29929943 0.95 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL30053231 0.95 SMN1; SMN2 (0.72) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL491308 0.93 SMN1; SMN2 (0.70) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL30358269 0.91 SMN1; SMN2 (0.69) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL3484768 0.91 SMN1; SMN2 (0.69) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1
SCHEMBL15834450 0.91 LTA4H (0.82) SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-06-25 US disclosed
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-06-25 US disclosed
US-20220153956-A1 Polyimide-Gold-Nanorod J-aggregates with Broadened Surface Plasmonic Resonance Band and Method of Manufacture GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2022-05-19 US disclosed
CN-110511533-B Polyether-ether-ketone/tetrafluoroethylene-perfluoroalkoxy vinyl ether copolymer/chopped quartz fiber material, and preparation method and application thereof 吉林大学 2020-08-04 CN disclosed
CN-110511533-A Polyether-ether-ketone/tetrafluoroethylene-perfluoro alkoxy vinyl ethers copolymer/be chopped silica fiber material, preparation method and application UNIV JILIN 2019-11-29 CN disclosed
EP-0135938-B1 PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES MITSUBISHI KASEI CORPORATION (JP) 1988-06-22 EP disclosed
US-4707536-A Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4661581-A REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-28 US disclosed
EP-0135938-A2 Process for producing aromatic polyether ketones and polythioether ketones MITSUBISHI KASEI CORPORATION (JP) 1985-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12017972-B2 All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom TPR, AS3MT, ASF1A SMN1; SMN2 3987/4885LTA4H 2586/4885MTNR1B 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.