Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | LTA4H | P09960 | 2/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608736 | 0.98 | SMN1; SMN2 (0.73) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL10709191 | 0.98 | SMN1; SMN2 (0.80) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL15834450 | 0.93 | LTA4H (0.82) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL13167638 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL1061713 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL30053231 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL29929943 | 0.93 | SMN1; SMN2 (0.72) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL491308 | 0.91 | SMN1; SMN2 (0.70) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL30358269 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL3484768 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2LTA4HMTNR1BMTNR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2024-06-25 | — | — | US | disclosed |
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2024-06-25 | — | — | US | disclosed |
| US-20220153956-A1 | Polyimide-Gold-Nanorod J-aggregates with Broadened Surface Plasmonic Resonance Band and Method of Manufacture | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2022-05-19 | — | — | US | disclosed |
| WO-2011118845-A1 | POLYESTER RESIN, AND OPTICAL MATERIALS, FILMS AND IMAGE DISPLAY DEVICES USING THE SAME | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | WO | disclosed |
| US-7541466-B2 | Tetrahydroisoquinoline derivatives for treating protein trafficking diseases | GENZYME CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| US-7368068-B2 | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| EP-0026991-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4269965-A | COMPRISING MONOMERS OF P-HYDROXYBENZOIC ACID, 3,4'-DIHYDROXYBENZOPHENONE OR TEREPHTHALOYLDI(3-METHYL-4-HYDROXYBENZENE, AND TEREPHTHALIC ACID; LUSTER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0026991-A1 | Aromatic polyester and filaments | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | TPR, AS3MT, ASF1A | SMN1; SMN2 3987/4885LTA4H 2586/4885MTNR1B 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.