SCHEMBL22230522

SCHEMBL22230522

Nc1cc[c]c(C2CC2)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6601193 0.77 CHEK1 (0.43)
SCHEMBL4075115 0.74 PTGS1 (0.31)
SCHEMBL458931 0.74
SCHEMBL457257 0.74 HTR2C (0.32)
SCHEMBL6446557 0.74
SCHEMBL19993860 0.74 CSNK2A1 (0.33)
SCHEMBL28299092 0.72 HDAC8 (0.38)
SCHEMBL1778645 0.71 KMO (0.40) HTT
SCHEMBL15063639 0.69 TRPA1 (0.32)
SCHEMBL2487380 0.69 DRD2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1187360-C Phosphonic acid derivs, having carboxypeptidase B inhibitory activity MEIJI SEIKA KAISHA (JP) 2005-02-02 CN claimed
CN-1373766-A Phosphonic acid derivatives having carboxypeptidase B inhibitory activity MEIJI SEIKA KAISHA (JP) 2002-10-09 CN claimed
WO-2020147702-A1 EGFR INHIBITORS, COMPOSITIONS AND METHODS THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2020-07-23 WO disclosed
CN-109071560-A Thienopyridine formamide as ubiquitin-specific protease inhibitor 福马治疗股份有限公司 2018-12-21 CN disclosed
CN-102971291-B Novel amide derivative and use thereof as medicine MITSUBISHI TANABE PHARMA CORP 2015-07-22 CN disclosed
CN-102971291-A Novel amide derivative and use thereof as medicine MITSUBISHI TANABE PHARMA CORP 2013-03-13 CN disclosed
CN-1187360-C Phosphonic acid derivs, having carboxypeptidase B inhibitory activity MEIJI SEIKA KAISHA (JP) 2005-02-02 CN disclosed
CN-1167692-C Aminothiazole derivatives and their use as CRF receptor ligands ʥŵ��-�ϳ�ʵ���ҹ�˾ 2004-09-22 CN disclosed
CN-1373766-A Phosphonic acid derivatives having carboxypeptidase B inhibitory activity MEIJI SEIKA KAISHA (JP) 2002-10-09 CN disclosed