Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230717 | 0.83 | MAPT (0.48) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL17338792 | 0.77 | KMT2A (0.50) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL22609299 | 0.75 | MEN1 (0.46) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL11782819 | 0.71 | GAA (0.46) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL696315 | 0.71 | KMT2A (0.57) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL28353412 | 0.71 | CES2 (0.47) | MAPTKMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL2204826 | 0.70 | ALDH1A1 (0.43) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL19398550 | 0.68 | LMNA (0.42) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL22993871 | 0.68 | KMT2A (0.54) | MAPTKMT2AMEN1S1PR4LMNA | |
| SCHEMBL1966571 | 0.68 | MAPT (0.54) | MAPTKMT2AMEN1S1PR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |