Sugi Predict

Sugi Predict / Compounds / SCHEMBL1966571

SCHEMBL1966571

SCHEMBL1966571

C=C(C(=O)OCC)c1ccc(Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ S1PR4 O95977 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ S1PR1 P21453 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ ALDH1A1 P00352 4/20 0.47
▸ HPGD P15428 2/20 0.47
▸ NHERF1 O14745 1/20 0.44
▸ SIRT2 Q8IXJ6 1/20 0.43
▸ CES2 O00748 2/20 0.43
▸ CES1 P23141 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ ACHE P22303 1/20 0.43
▸ TARBP2 Q15633 1/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5059081 0.91 MAPT (0.55) MAPTKMT2AMEN1S1PR4LMNA
SCHEMBL27759974 0.86 ALDH1A1 (0.45) MAPTKMT2AMEN1S1PR4LMNA
SCHEMBL5086187 0.85 ALDH1A1 (0.50) MAPTKMT2ALMNAALDH1A1HPGD
SCHEMBL2491603 0.84 CA12 (0.61) MAPTKMT2AMEN1LMNAMAPK1
SCHEMBL6718454 0.84 ALDH1A1 (0.53) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL11810314 0.83 MAPT (0.42) MAPTKMT2AMEN1S1PR4LMNA
SCHEMBL5643285 0.82 ALDH1A1 (0.47) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL5626568 0.82 LMNA (0.62) MAPTKMT2AMEN1LMNANPSR1
SCHEMBL9141441 0.82 MAPT (0.54) MAPTKMT2AMEN1LMNAMAPK1
SCHEMBL7079697 0.82 SMN1; SMN2 (0.53) MAPTKMT2AMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 — — CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 — — CN claimed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 — — CN claimed
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2026-04-21 — — US disclosed
EP-4651872-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS Septerna, Inc. (US) 2025-11-26 — — EP disclosed
US-20240398959-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2024-12-05 — — US disclosed
WO-2024155601-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS SEPTERNA, INC. (US) 2024-07-25 — — WO disclosed
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2024-05-28 — — US disclosed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 — — CN disclosed
US-11839613-B2 Pyrimidine derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2023-12-12 — — US disclosed
EP-4261211-A1 DIHYDROISOQUINOLINONE DERIVATIVE AND APPLICATION THEREOF Etern Biopharma (Shanghai) Co., Ltd. (CN) 2023-10-18 — — EP disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 — — US disclosed
EP-1791901-A2 STABILIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2007-06-06 — — EP disclosed
WO-2006024611-A2 STABILIZATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-09 — — WO disclosed
EP-1212309-B1 CASPASE INHIBITOR LG CHEM INVESTMENT LTD (KR) 2004-08-18 — — EP disclosed
US-6747050-B1 INHIBITING THE ACTIVITY OF CASPASES, PREVENTING INFLAMMATION AND APOPTOSIS LG CHEM INVESTMENT LTD. (KR) 2004-06-08 — — US disclosed
EP-1212309-A4 CASPASE INHIBITOR LG CHEM INVESTMENT LTD (KR) 2002-11-27 — — EP disclosed
EP-1212309-A1 CASPASE INHIBITOR LG Chem Investment, Ltd. (KR) 2002-06-12 — — EP disclosed
WO-2001021600-A1 CASPASE INHIBITOR LG CHEM INVESTMENT LTD. (KR) 2001-03-29 — — WO disclosed
WO-2001021599-A1 CASPASE INHIBITOR LG CHEMICAL LTD. (KR) 2001-03-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation NEDD4, UBE3A, UBE3C MAPT 4032/4885KMT2A 2907/4885MEN1 2648/4885
US-11839613-B2 Pyrimidine derivatives as PGE2 receptor modulators PTGER1, PTGER4, PTGER2 MAPT 4627/4885KMT2A 2391/4885MEN1 4485/4885
US-11992531-B2 C3-carbon linked glutarimide degronimers for target protein degradation STUB1, UBE3C, UBE3A MAPT 2494/4885KMT2A 2966/4885MEN1 1031/4885
US-20240398959-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, UBE3A MAPT 2494/4885KMT2A 2966/4885MEN1 1031/4885
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 MAPT 128/4885KMT2A 1853/4885MEN1 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.