SCHEMBL222311

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2760411	0.77	PIK3CD (0.57)	PIK3CDPIK3CAPI4KAPI4KBPIP5K1C
	SCHEMBL1359845	0.76	CYP2A6 (0.57)	CYP2A6NPC1RAB9ASMN1; SMN2TP53
	SCHEMBL221757	0.76	—	—
	SCHEMBL220914	0.75	SMN1; SMN2 (0.50)	PIK3CAPIK3CGNPC1RAB9ASMN1; SMN2
	SCHEMBL13785066	0.75	CYP2A6 (0.64)	PIK3CACYP2A6NPC1RAB9ASMN1; SMN2
	SCHEMBL12264114	0.74	PIK3CD (0.53)	PIK3CDPIK3CAPI4KAPI4KBPIP5K1C
	SCHEMBL12509852	0.74	PIK3CA (0.56)	PIK3CDPIK3CAPI4KAPI4KBPIP5K1C
	SCHEMBL29013271	0.74	PIK3CD (0.55)	PIK3CDPIK3CAPI4KAPI4KBPIK3CG
	SCHEMBL189244	0.72	ASH1L (0.59)	PIK3CDPIK3CAPI4KAPI4KBPIP5K1C
	SCHEMBL222987	0.72	PIK3CD (0.51)	PIK3CDPIK3CAPI4KAPI4KBPIP5K1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.