Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516426 | 0.89 | KDM4E (0.38) | GABRG2GABRB3GABRA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16748720 | 0.86 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL2364441 | 0.82 | STK17B (0.40) | ALDH1A1MAPTKDM4EHPGDGLA | |
| SCHEMBL16748721 | 0.77 | SIRT5 (0.39) | GABRG2GABRB3GABRA2ALDH1A1KDM4E | |
| SCHEMBL15793420 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL15803548 | 0.71 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2CA12CA14KDM4E | |
| SCHEMBL16748723 | 0.70 | STK17B (0.41) | ALDH1A1MAPTKDM4EHPGDGLA | |
| SCHEMBL16748713 | 0.69 | GABRG2 (0.41) | GABRG2GABRB3GABRA2GABRA1GABRA5 | |
| SCHEMBL12206551 | 0.69 | ABCB11 (0.35) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL13531612 | 0.68 | STK17B (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084571-A2 | AZIDE DERIVATIVES FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011084571-A2 | AZIDE DERIVATIVES FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-07-14 | — | — | WO | disclosed |