Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CEPT1 | Q9Y6K0 | 8/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 9/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222186 | 0.91 | S1PR1 (0.48) | S1PR1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2223699 | 0.88 | S1PR1 (0.45) | S1PR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2225559 | 0.87 | S1PR1 (0.49) | S1PR1MAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL2222985 | 0.86 | S1PR1 (0.52) | S1PR1MAPTCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2224286 | 0.86 | S1PR1 (0.54) | S1PR1MAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2222292 | 0.85 | S1PR1 (0.44) | S1PR1 | |
| SCHEMBL2223599 | 0.85 | S1PR1 (0.47) | S1PR1MAPTCEPT1RXFP1CETP | |
| SCHEMBL2269044 | 0.84 | S1PR1 (0.55) | S1PR1MAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2222541 | 0.84 | S1PR1 (0.51) | S1PR1MAPTALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14797136 | 0.84 | S1PR1 (0.71) | S1PR1MAPTCEPT1RXFP1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |