Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235400 | 0.92 | KDM4E (0.31) | MEN1KMT2AATM | |
| SCHEMBL22235411 | 0.80 | — | — | |
| SCHEMBL22235323 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL29728936 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL22235440 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL22235484 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2A | |
| SCHEMBL22235409 | 0.70 | GABRA1 (0.35) | MEN1KMT2AATM | |
| SCHEMBL22235343 | 0.70 | GABRA1 (0.35) | MEN1KMT2AATM | |
| SCHEMBL22235514 | 0.70 | GABRA1 (0.35) | MEN1KMT2AATM | |
| SCHEMBL29728904 | 0.70 | GABRA1 (0.35) | MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911653-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2021-11-24 | — | — | EP | claimed |
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | claimed |
| EP-3911653-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |