⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235460 | 0.87 | — | — | |
| SCHEMBL22236138 | 0.82 | — | — | |
| SCHEMBL22235325 | 0.80 | MEN1 (0.30) | — | |
| SCHEMBL22235400 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL22235409 | 0.71 | GABRA1 (0.35) | — | |
| SCHEMBL22235514 | 0.71 | GABRA1 (0.35) | — | |
| SCHEMBL22235343 | 0.71 | GABRA1 (0.35) | — | |
| SCHEMBL29728904 | 0.71 | GABRA1 (0.35) | — | |
| SCHEMBL22235440 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL22235484 | 0.68 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911653-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150366-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-07-23 | — | — | WO | disclosed |