Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043365 | 0.86 | PLK1 (0.55) | HDAC6HDAC1HDAC4HDAC2HDAC10 | |
| SCHEMBL22692894 | 0.84 | HPGDS (0.46) | KDM4EL3MBTL1HDAC6HDAC1HCAR3 | |
| SCHEMBL16560322 | 0.82 | MAOB (0.51) | BLMPMP22KDM4ECYP1A2MEN1 | |
| SCHEMBL5293898 | 0.81 | NNMT (0.55) | KDM4EL3MBTL1 | |
| SCHEMBL12388320 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1KMT2ARAB9A | |
| SCHEMBL27981651 | 0.81 | HCAR3 (0.42) | MAPTALDH1A1LMNAKMT2ARAB9A | |
| SCHEMBL14023317 | 0.81 | KCNJ1 (0.45) | MAPTLMNAL3MBTL1KMT2ARAB9A | |
| SCHEMBL16560318 | 0.80 | KDM4E (0.50) | MAPTHIF1ACA1CA2KDM4E | |
| SCHEMBL30024043 | 0.80 | CASP3 (0.43) | MAPTMPOCYP3A4KDM5ABLM | |
| SCHEMBL344135 | 0.79 | MAPT (0.58) | MAPTALDH1A1CYP1A2CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |