Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HINT1 | P49773 | 3/20 | 0.38 |
| ▸ | AMD1 | P17707 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21461828 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL21475718 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL21475719 | 0.90 | KDM4E (0.50) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL15828296 | 0.88 | KDM4E (0.51) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL22236567 | 0.88 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL25401028 | 0.88 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL3313609 | 0.88 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL15588764 | 0.88 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1RXFP1PI4KA | |
| SCHEMBL25404255 | 0.88 | TAS1R3 (0.64) | KDM4ETAS1R3TAS1R1P2RX1P2RX3 | |
| SCHEMBL15588763 | 0.83 | RXFP1 (0.47) | KDM4ETAS1R3TAS1R1RXFP1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717758-B2 | D-amino acid compounds for liver disease | IDENIX PHARMACEUTICALS LLC (US) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717758-B2 | D-amino acid compounds for liver disease | AADAT, BCAT1, BCAT2 | KDM4E 2229/4885TAS1R3 4618/4885TAS1R1 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.